Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.59 |
| ▸ | MEN1 | O00255 | 13/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 3/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671088 | 1.00 | MAPT (0.63) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL29803551 | 0.82 | KMT2A (0.59) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL24670571 | 0.82 | KMT2A (0.59) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL4022371 | 0.81 | LMNA (0.59) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL12443478 | 0.81 | KMT2A (0.72) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL31337210 | 0.79 | ESR1 (0.64) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL24670582 | 0.79 | KMT2A (0.57) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL29803339 | 0.79 | KMT2A (0.57) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL24669279 | 0.78 | KMT2A (0.61) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL24671107 | 0.76 | MAPT (0.90) | MAPTKMT2AMEN1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |