Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 13/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595202 | 1.00 | ROCK2 (0.67) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28587953 | 0.90 | ROCK2 (0.66) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29804160 | 0.90 | ROCK2 (0.66) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29804548 | 0.85 | ROCK2 (0.64) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28582501 | 0.85 | ROCK2 (0.64) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28584472 | 0.81 | ROCK2 (0.64) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29804537 | 0.81 | ROCK2 (0.64) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29804283 | 0.81 | ROCK2 (0.63) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20511561 | 0.81 | ROCK2 (0.69) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21128159 | 0.80 | ROCK2 (1.00) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961081-B | Bibenzamide urea compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-13 | — | — | CN | disclosed |