Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177356 | 1.00 | TDP1 (0.44) | TDP1SMN1; SMN2HAO1KMT2AL3MBTL1 | |
| SCHEMBL177455 | 0.79 | CYP3A4 (0.45) | SMN1; SMN2KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL450533 | 0.79 | MRGPRX4 (0.39) | KMT2AL3MBTL1ALDH1A1NPC1SLC6A4 | |
| SCHEMBL177406 | 0.79 | MCL1 (0.49) | TDP1SMN1; SMN2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14660398 | 0.79 | TSHR (0.45) | TDP1SMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL177568 | 0.79 | HTR2A (0.40) | KMT2AHTR2ASLC6A4RAB9A | |
| SCHEMBL1124557 | 0.79 | ALDH1A1 (0.48) | TDP1SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL23744 | 0.78 | CA12 (0.45) | SMN1; SMN2KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL23052 | 0.78 | CA12 (0.45) | TDP1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2314642 | 0.78 | SMN1; SMN2 (0.33) | TDP1SMN1; SMN2HAO1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111108148-B | Treatment additives for silicone elastomer bases | 美国陶氏有机硅公司 | 2022-08-23 | — | — | CN | claimed |
| CN-111108148-B | Treatment additives for silicone elastomer bases | 美国陶氏有机硅公司 | 2022-08-23 | — | — | CN | disclosed |