Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.79 |
| ▸ | NPY2R | P49146 | 3/20 | 0.79 |
| ▸ | NPY4R | P50391 | 3/20 | 0.79 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.61 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.61 |
| ▸ | KISS1R | Q969F8 | 9/20 | 0.60 |
| ▸ | MC4R | P32245 | 2/20 | 0.56 |
| ▸ | MC1R | Q01726 | 2/20 | 0.56 |
| ▸ | MC5R | P33032 | 1/20 | 0.56 |
| ▸ | MC3R | P41968 | 1/20 | 0.56 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.55 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797506 | 1.00 | NPY1R (0.79) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL29392504 | 0.96 | NPY1R (0.75) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL29373777 | 0.90 | NPY1R (0.74) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL29390038 | 0.90 | NPY1R (0.67) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL29426680 | 0.90 | NPY1R (0.68) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL29738308 | 0.90 | ERAP2 (0.73) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL29924773 | 0.90 | ERAP2 (0.73) | NPY1RNPY2RNPY4RERAP2ERAP1 | |
| SCHEMBL31202576 | 0.88 | GHSR (0.66) | NPY1RNPY2RNPY4R | |
| SCHEMBL22597783 | 0.86 | NPY1R (0.65) | NPY1RNPY2RNPY4RKISS1RMC4R | |
| SCHEMBL22597782 | 0.86 | NPY1R (0.65) | NPY1RNPY2RNPY4RKISS1RMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305088-A1 | METHODS AND COMPOSITIONS FOR TREATING A MICROBIAL INFECTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-09-29 | — | — | US | disclosed |
| US-11400136-B2 | Methods and compositions for treating a microbial infection | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-08-02 | — | — | US | disclosed |