Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19125667 | 1.00 | KMT2A (0.46) | KMT2ALMNANPC1RAB9ANPSR1 | |
| SCHEMBL19125377 | 0.83 | NPC1 (0.46) | KMT2ALMNANPC1RAB9ANPSR1 | |
| SCHEMBL29155388 | 0.81 | RXRA (0.51) | KMT2AKCNK9NR1H4KIF11RXRA | |
| SCHEMBL28403846 | 0.80 | SRD5A2 (0.54) | KMT2ALMNANPC1RAB9APOLB | |
| SCHEMBL27313443 | 0.79 | HDAC3 (0.50) | KMT2ANPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL1628254 | 0.78 | AKR1C3 (0.50) | KMT2APKMKIF11KCNH2AKR1C2 | |
| SCHEMBL28739477 | 0.77 | CYP19A1 (0.45) | KMT2ANPC1RAB9AKIF11 | |
| SCHEMBL1625391 | 0.77 | MEN1 (0.54) | KMT2ANPC1RAB9ANPSR1POLB | |
| Methyl Alcohol SCHEMBL27512784 | 0.77 | HDAC4 (0.48) | KMT2ALMNANPC1RAB9ANPSR1 | |
| SCHEMBL78619 | 0.76 | HDAC4 (0.47) | KMT2ALMNANPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698991-B | 2-oxoindole compound | 凯莫森特里克斯股份有限公司 | 2022-08-23 | — | — | CN | disclosed |