Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898314 | 0.97 | CAPN1 (0.44) | CALCRLACERENCAPN1BACE1 | |
| SCHEMBL30362861 | 0.91 | CALCRL (0.40) | CALCRLCAPN1SLC6A2KMT2AL3MBTL1 | |
| SCHEMBL29590352 | 0.84 | BACE1 (0.46) | CALCRLACERENBACE1CTSD | |
| SCHEMBL30658578 | 0.84 | CALCRL (0.49) | CALCRLACERENBACE1CTSD | |
| SCHEMBL30957276 | 0.83 | ACE (0.60) | ACERENSLC6A2F2 | |
| SCHEMBL31696336 | 0.82 | XIAP (0.47) | F2XIAP | |
| SCHEMBL29805559 | 0.82 | BACE1 (0.47) | BACE1CTSD | |
| SCHEMBL29630627 | 0.81 | ACE (0.49) | ACERENBACE1CTSDXIAP | |
| SCHEMBL30436048 | 0.81 | ACE (0.51) | ACERENF2 | |
| SCHEMBL30997445 | 0.80 | CAPN1 (0.48) | CALCRLACERENCAPN1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116159024-A | Beta-hairpin peptidomimetics having elastase inhibitory activity and aerosol dosage forms thereof | 思帕克塞斯股份公司 | 2023-05-26 | — | — | CN | claimed |
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | claimed |
| CN-116159024-A | Beta-hairpin peptidomimetics having elastase inhibitory activity and aerosol dosage forms thereof | 思帕克塞斯股份公司 | 2023-05-26 | — | — | CN | disclosed |
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | disclosed |