Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.37 |
| ▸ | CALCR | P30988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805727 | 0.97 | CALCRL (0.46) | CAPN1CALCRLACERENCTSD | |
| SCHEMBL30362861 | 0.88 | CALCRL (0.40) | CAPN1CALCRLSLC6A2KMT2AL3MBTL1 | |
| SCHEMBL29362259 | 0.85 | NPY2R (0.47) | F2RAMP3CALCR | |
| SCHEMBL29805251 | 0.85 | NPY2R (0.47) | F2RAMP3CALCR | |
| SCHEMBL29590352 | 0.82 | BACE1 (0.46) | CALCRLACERENCTSDBACE1 | |
| SCHEMBL30658578 | 0.81 | CALCRL (0.49) | CALCRLACERENCTSDBACE1 | |
| SCHEMBL29765215 | 0.80 | ACE (0.52) | CAPN1ACERENCTSBF2 | |
| SCHEMBL29765157 | 0.80 | ACE (0.52) | CAPN1ACERENCTSBF2 | |
| SCHEMBL30957276 | 0.80 | ACE (0.60) | ACERENF2SLC6A2 | |
| SCHEMBL31696336 | 0.79 | XIAP (0.47) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3463281-B1 | BETA-HAIRPIN PEPTIDOMIMETIC WITH ELASTASE INHIBITORY ACTIVITY AND AEROSOL DOSAGE FORMS THEREOF | POLYPHOR AG (CH) | 2022-07-06 | — | — | EP | disclosed |