Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.47 |
| ▸ | CDK2 | P24941 | 7/20 | 0.47 |
| ▸ | CCNK | O75909 | 5/20 | 0.47 |
| ▸ | CDK9 | P50750 | 5/20 | 0.47 |
| ▸ | CCND3 | P30281 | 4/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26617105 | 0.83 | PTK2 (0.59) | ULK1CDK9ALK | |
| SCHEMBL29805915 | 0.83 | PTK2 (0.59) | ULK1CDK9ALK | |
| SCHEMBL29190692 | 0.81 | ULK1 (0.58) | ULK1CDK1KDRCCNA2CDK2 | |
| SCHEMBL30833798 | 0.81 | ULK1 (0.58) | ULK1CDK1KDRCCNA2CDK2 | |
| SCHEMBL29806050 | 0.81 | CCNA2 (0.59) | ULK1CCNA2CDK2CCNKCDK9 | |
| SCHEMBL29190707 | 0.80 | ALK (0.52) | ULK1CCNA2CDK2CCNKCDK9 | |
| SCHEMBL30833625 | 0.80 | ALK (0.52) | ULK1CCNA2CDK2CCNKCDK9 | |
| SCHEMBL29805878 | 0.79 | MAPK8 (0.46) | ULK1CDK1KDRCCNA2CDK2 | |
| SCHEMBL29805837 | 0.79 | CCNA2 (0.47) | ULK1KDRCCNA2CDK2CCNK | |
| SCHEMBL30833650 | 0.78 | LRRK2 (0.48) | ULK1CCNA2CDK2CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829344-A | Novel pyrimidine derivative and use thereof | 韩国化学研究院 | 2022-07-29 | — | — | CN | claimed |
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | disclosed |
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | disclosed |
| CN-114829344-A | Novel pyrimidine derivative and use thereof | 韩国化学研究院 | 2022-07-29 | — | — | CN | disclosed |