SCHEMBL29807129

SCHEMBL29807129

Cc1cc2c(O)cccc2[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
RXFP1 Q9HBX9 2/20 0.50
CYP1A2 P05177 1/20 0.50
DAO P14920 5/20 0.49
DDO Q99489 4/20 0.49
IMPDH2 P12268 1/20 0.47
IMPDH1 P20839 1/20 0.47
NQO2 P16083 1/20 0.46
HRH4 Q9H3N8 1/20 0.45
ABCB11 O95342 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933745 1.00 GAA (0.50) GAARXFP1CYP1A2DAODDO
SCHEMBL27851993 0.83 GAA (0.47) GAARXFP1CYP1A2DAODDO
SCHEMBL12755282 0.79 IMPDH2 (0.43) DAODDOIMPDH2IMPDH1HRH4
SCHEMBL8230643 0.78 DAO (0.56) GAARXFP1CYP1A2DAODDO
SCHEMBL29713806 0.78 DAO (0.56) GAARXFP1CYP1A2DAODDO
SCHEMBL3186919 0.76 GAA (0.47) GAARXFP1CYP1A2DAODDO
SCHEMBL1353956 0.75 PARP1 (0.59) GAARXFP1CYP1A2NQO2HRH4
SCHEMBL12778107 0.75 IMPDH2 (0.47) CYP1A2DAODDOIMPDH2IMPDH1
SCHEMBL15373471 0.75 NR1I2 (0.51) GAARXFP1CYP1A2NQO2KDM4E
SCHEMBL1650595 0.75 CYP1A2 (0.55) GAARXFP1CYP1A2DAODDO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021120-A1 5-HT2A RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2025-01-30 WO disclosed
EP-4277892-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS Les Laboratoires Servier (FR) 2023-11-22 EP disclosed
WO-2022152705-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS LES LABORATOIRES SERVIER (FR) 2022-07-21 WO disclosed