SCHEMBL298080

SCHEMBL298080

CCC(SSCC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.38
POLB P06746 2/20 0.36
HIF1A Q16665 1/20 0.35
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
BLM P54132 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 1/20 0.32
FFAR3 O14843 1/20 0.32
ALDH1A1 P00352 1/20 0.31
FOLH1 Q04609 1/20 0.31
CA2 P00918 1/20 0.30
MAPK1 P28482 1/20 0.30
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1359176 0.81 HTT (0.45) HTTPOLBTP53CYP1A2FFAR3
SCHEMBL30039089 0.77 GPR84 (0.47) POLBGMNNTP53MAPTTHRB
SCHEMBL6239079 0.77 HTT (0.40) CYP2D6CYP2C19HTTPOLBHIF1A
SCHEMBL15751072 0.77 HTT (0.42) HTTPOLBCYP1A2FFAR3ALDH1A1
SCHEMBL13772960 0.76 POLB (0.39) CYP2C19HTTPOLBCYP2C9ALDH1A1
SCHEMBL20483349 0.75 HTT (0.36) HTTPOLBMAPTALDH1A1TDP1
SCHEMBL29277015 0.74 GPR84 (0.43) POLBGMNNTP53MAPTTHRB
SCHEMBL31711248 0.74 GPR84 (0.43) POLBGMNNTP53MAPTTHRB
SCHEMBL6584919 0.72
SCHEMBL1574284 0.71 HTT (0.45) HTTPOLBTP53CYP1A2FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170110759-A1 SOLID ELECTROLYTE BASF SE (DE) 2017-04-20 US disclosed
EP-3120408-A1 SOLID ELECTROLYTE BASF SE (DE) 2017-01-25 EP disclosed
WO-2015140298-A1 SOLID ELECTROLYTE BASF SE (DE) 2015-09-24 WO disclosed
EP-1506240-B1 GRAFT POLYOLS PREPARED BY A CONTINUOUS PROCESS BASF CORP (US) 2012-03-14 EP disclosed
EP-1641852-B1 PROCESS FOR FORMATION OF PREFORMED STABILIZER POLYOLS BASF CORP (US) 2008-07-23 EP disclosed
US-7148288-B2 Process for formation of preformed stabilizer polyols BASF CORPORATION (US) 2006-12-12 US disclosed
EP-1506240-A1 GRAFT POLYOLS PREPARED BY A CONTINUOUS PROCESS BASF CORPORATION (US) 2005-02-16 EP disclosed
US-20040266958-A1 Process for formation of preformed stabilizer polyols BASF CORPORATION 2004-12-30 US disclosed
US-6780932-B2 Graft polyols prepared by a continuous process BASF CORPORATION 2004-08-24 US disclosed
WO-2003097710-A1 GRAFT POLYOLS PREPARED BY A CONTINUOUS PROCESS BASF CORPORATION (US) 2003-11-27 WO disclosed
US-4689354-A STYRENE GRAFTED POLYESTERETHER POLYOLS, CHAIN TRANSFERAGENTS, UNSATURATION BASF CORPORATION (US) 1987-08-25 US disclosed
US-4661531-A IN SITU FREE RADICAL POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMER IN POLYOL BASF CORPORATION (US) 1987-04-28 US disclosed
US-4568705-A HIGH RESILIENT POLYETHER-AND ESTERURETHANES BASF WYANDOTTE CORPORATION (US) 1986-02-04 US disclosed
EP-0163188-A2 A graft polymer dispersion in a mixture of low molecular weight polyols and polyether polyols and polyurethane foams prepared therefrom BASF Corporation (US) 1985-12-04 EP disclosed
US-4555527-A POLYURETHANE FOAM BASF WYANDOTTE CORPORATION (US) 1985-11-26 US disclosed
US-4522976-A Graft polymer dispersion in a mixture of low molecular weight polyols and polyether polyols and polyurethane foams prepared therefrom BASF WYANDOTTE CORPORATION (US) 1985-06-11 US disclosed
US-4503207-A UNSATURATION-CONTAINING POLYOLS BASF WYANDOTTE CORPORATION (US) 1985-03-05 US disclosed
US-4458038-A ADDITION-CONDENSATION COPOLYMERS BASF WYANDOTTE CORPORATION (US) 1984-07-03 US disclosed
US-4454255-A 0.001 TO 0.09 MOLE OF INDUCED UNSATURATION PER MOLE OF POLYOL MIXTURE BASF WYANDOTTE CORPORATION (US) 1984-06-12 US disclosed
EP-0091036-A2 Process for the preparation of white graft polymer dispersions and flame-retardant polyurethane foams BASF Corporation (US) 1983-10-12 EP disclosed