Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365998 | 0.85 | SIGMAR1 (0.43) | CHRM5CHRM3HSD17B10SIGMAR1 | |
| SCHEMBL30821481 | 0.84 | CHRM5 (0.34) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL472213 | 0.84 | CHRM5 (0.50) | CHRM5CHRM3HSD17B10SIGMAR1SLC6A9 | |
| SCHEMBL29299554 | 0.84 | CHRM5 (0.50) | CHRM5CHRM3HSD17B10SIGMAR1SLC6A9 | |
| SCHEMBL306395 | 0.84 | CHRM5 (0.50) | CHRM5CHRM3HSD17B10SIGMAR1SLC6A9 | |
| SCHEMBL8038178 | 0.82 | CHRM5 (0.48) | CHRM5CHRM3HSD17B10SIGMAR1ALDH1A1 | |
| SCHEMBL6537424 | 0.82 | CHRM5 (0.48) | CHRM5CHRM3HSD17B10SIGMAR1SLC6A9 | |
| SCHEMBL5550813 | 0.82 | CHRM5 (0.48) | CHRM5CHRM3HSD17B10SIGMAR1SLC6A9 | |
| SCHEMBL10567168 | 0.82 | CHRM5 (0.48) | CHRM5CHRM3HSD17B10SIGMAR1SLC6A9 | |
| Hydrochloric Acid SCHEMBL28968883 | 0.82 | CHRM5 (0.48) | CHRM5CHRM3HSD17B10SIGMAR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4277663-A1 | ACTIVE DELIVERY OF RADIOTRACERS ACROSS THE BLOOD BRAIN BARRIER | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023057034-A1 | FIBRONECTIN-BINDING PEPTIDES FOR USE IN TUMOR OR FIBROSIS DIAGNOSIS AND THERAPY | ETH Zürich (CH) | 2023-04-13 | — | — | WO | disclosed |
| WO-2022155499-A1 | ACTIVE DELIVERY OF RADIOTRACERS ACROSS THE BLOOD BRAIN BARRIER | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-07-21 | — | — | WO | disclosed |