SCHEMBL29808596

SCHEMBL29808596

Nc1nc(N)c2ncn([C@H]3C[C@H](O)[C@@H](COP(=O)(O)O)O3)c2n1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.72
POLB P06746 2/20 0.65
ENPP1 P22413 3/20 0.59
P2RY1 P47900 3/20 0.59
PDE4D Q08499 2/20 0.58
PDE3A Q14432 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
PNP P00491 1/20 0.58
LMNA P02545 1/20 0.58
TP53 P04637 1/20 0.58
HTT P42858 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
CA5A P35218 1/20 0.57
DNPH1 O43598 1/20 0.52
PRKAB2 O43741 1/20 0.52
TRPM2 O94759 1/20 0.52
LDHA P00338 1/20 0.52
ADRB2 P07550 1/20 0.52
FBP1 P09467 1/20 0.52
SRC P12931 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207372 1.00 NT5E (0.72) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL17117807 1.00 NT5E (0.72) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL12932286 0.91 NT5E (0.67) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL29400356 0.91 NT5E (0.67) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL345288 0.91 NT5E (0.67) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL19389361 0.91 NT5E (0.67) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL4820794 0.91 NT5E (0.67) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL17117823 0.91 NT5E (0.67) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL23501737 0.91 NT5E (0.63) NT5EPOLBENPP1P2RY1PDE4D
SCHEMBL285024 0.90 NT5E (0.84) NT5EPOLBENPP1P2RY1PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955843-A CAS mediated homeotropic repair in somatic plant tissue 先锋国际良种公司 2025-05-09 CN disclosed
EP-4548351-A1 ARTIFICIAL INTELLIGENCE-MEDIATED METHODS AND SYSTEMS FOR GENOME EDITING Pioneer Hi-Bred International, Inc. (US) 2025-05-07 EP disclosed
CN-119698471-A CAS endonuclease and guide RNA variants with improved efficiency 先锋国际良种公司 2025-03-25 CN disclosed
CN-113166744-B Novel CRISPR-CAS system for genome editing 先锋国际良种公司 2025-02-07 CN disclosed
CN-115243711-B Two-step gene exchange 先锋国际良种公司 2024-12-17 CN disclosed
CN-113939594-B Embryogenic factors for cell reprogramming of plant cells 先锋国际良种公司 2024-12-17 CN disclosed
CN-112020554-B Novel CAS9 orthologs 先锋国际良种公司 2024-10-22 CN disclosed
CN-114836399-B Process for preparing isoguanine deoxyribonucleotide 天津大学 2024-07-05 CN disclosed
CN-117431234-A Peptides and nanoparticles for intracellular delivery of genome editing molecules 阿迪根有限公司 2024-01-23 CN disclosed
WO-2024006802-A1 ARTIFICIAL INTELLIGENCE-MEDIATED METHODS AND SYSTEMS FOR GENOME EDITING PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 WO disclosed
CN-116635529-A Double haploid inducer 先锋国际良种公司 2023-08-22 CN disclosed
CN-116456824-A Parthenogenesis factors and methods of use thereof 先锋国际良种公司 2023-07-18 CN disclosed
CN-110295246-B Loci associated with response to abiotic stress 纳幕尔杜邦公司 2023-06-27 CN disclosed
CN-116249780-A Rapid transformation of monocot leaf explants 先锋国际良种公司 2023-06-09 CN disclosed
CN-115698302-A Large-scale genome manipulation 先锋国际良种公司 2023-02-03 CN disclosed
EP-4102961-A1 METHODS AND COMPOSITIONS FOR MULTIPLEXED EDITING OF PLANT CELL GENOMES Pioneer Hi-Bred International Inc. (US) 2022-12-21 EP disclosed
CN-115135143-A Methods and compositions for multiplex editing of plant cell genomes 先锋国际良种公司 2022-09-30 CN disclosed
CN-114836399-A Preparation method of isoguanine deoxyribonucleotide 天津大学 2022-08-02 CN disclosed
CN-114836400-A Enzyme participating in synthesis of bacteriophage diaminopurine and application thereof 天津大学 2022-08-02 CN disclosed
CN-108368517-B Methods and compositions for rapid plant transformation 先锋国际良种公司 2022-08-02 CN disclosed