Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PNP | P00491 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808596 | 1.00 | NT5E (0.72) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL17117807 | 1.00 | NT5E (0.72) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL12932286 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL29400356 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL345288 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL19389361 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL4820794 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL17117823 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL23501737 | 0.91 | NT5E (0.63) | NT5EPOLBENPP1P2RY1PDE4D | |
| SCHEMBL285024 | 0.90 | NT5E (0.84) | NT5EPOLBENPP1P2RY1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624059-A2 | Method of producing nucleic acid molecules with reduced secondary structure | Agilent Technologies, Inc. (US) | 2006-02-08 | — | — | EP | claimed |
| US-20040086880-A1 | Method of producing nucleic acid molecules with reduced secondary structure | AGILENT TECHNOLOGIES, INC. | 2004-05-06 | — | — | US | claimed |
| US-20230059753-A1 | ANTISENSE GUIDE RNA WITH ADDED FUNCTIONAL REGION FOR EDITING TARGET RNA | ASTELLAS PHARMA INC. (JP) | 2023-02-23 | — | — | US | disclosed |
| EP-4074825-A1 | ANTISENSE GUIDE RNA WITH ADDED FUNCTIONAL REGION FOR EDITING TARGET RNA | Astellas Pharma Inc. (JP) | 2022-10-19 | — | — | EP | disclosed |
| CN-114787357-A | Antisense guide RNA to which functional region is added for editing target RNA | 安斯泰来制药株式会社 | 2022-07-22 | — | — | CN | disclosed |
| WO-2021117729-A1 | ANTISENSE GUIDE RNA WITH ADDED FUNCTIONAL REGION FOR EDITING TARGET RNA | アステラス製薬株式会社 | 2021-06-17 | — | — | WO | disclosed |
| US-7682809-B2 | Direct ATP release sequencing | AGILENT TECHNOLOGIES, INC. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20090181374-A1 | DIRECT ATP RELEASE SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2009-07-16 | — | — | US | disclosed |
| EP-1624059-A2 | Method of producing nucleic acid molecules with reduced secondary structure | Agilent Technologies, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| US-20040086880-A1 | Method of producing nucleic acid molecules with reduced secondary structure | AGILENT TECHNOLOGIES, INC. | 2004-05-06 | — | — | US | disclosed |