SCHEMBL29808715

SCHEMBL29808715

N=C(N)NCCCC[C@H](N)C(=O)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.42
▸ ALOX15 P16050 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ GNAI3 P08754 1/20 0.41
▸ GNAO1 P09471 1/20 0.41
▸ GNAI1 P63096 1/20 0.41
▸ NPY4R P50391 6/20 0.36
▸ NPY1R P25929 5/20 0.36
▸ NPY2R P49146 4/20 0.36
▸ NPY5R Q15761 4/20 0.36
▸ RRM1 P23921 1/20 0.36
▸ OTC P00480 1/20 0.35
▸ GSR P00390 1/20 0.33
▸ DDAH1 O94760 1/20 0.33
▸ NOS3 P29474 1/20 0.33
▸ NOS1 P29475 1/20 0.33
▸ NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10483768 0.95 DPP7 (0.40) DPP7ALOX15MEN1CYP1A2KMT2A
SCHEMBL31198211 0.95 DPP7 (0.40) DPP7ALOX15MEN1CYP1A2KMT2A
SCHEMBL5156455 0.85 DPP7 (0.44) DPP7ALOX15MEN1CYP1A2KMT2A
SCHEMBL21467496 0.85 DPP7 (0.44) DPP7ALOX15MEN1CYP1A2KMT2A
SCHEMBL28754154 0.84 GSR (0.52) ALOX15CYP1A2KMT2AOTCGSR
SCHEMBL10071054 0.84 GSR (0.52) ALOX15CYP1A2KMT2AOTCGSR
SCHEMBL27615800 0.84 GSR (0.52) ALOX15CYP1A2KMT2AOTCGSR
Hydrochloric Acid SCHEMBL2718693 0.84 DPP7 (0.43) DPP7ALOX15MEN1CYP1A2KMT2A
SCHEMBL880728 0.84 GSR (0.52) ALOX15CYP1A2KMT2AOTCGSR
SCHEMBL43287 0.84 GSR (0.52) ALOX15CYP1A2KMT2AOTCGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583900-B2 Peptide conjugates and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2026-03-24 — — US disclosed
CN-114561405-B Application of synthetic gene cluster of trichoderma Harzianolide in preparation of preparation for improving plant gray mold resistance 南京农业大学 2023-07-18 — — CN disclosed
US-20230071371-A1 PEPTIDE CONJUGATES AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2023-03-09 — — US disclosed
CN-114561405-A Application of synthetic gene cluster of trichoderma Harzianolide in preparation of preparation for improving plant gray mold resistance 南京农业大学 2022-05-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583900-B2 Peptide conjugates and methods of use GIPR, GLP1R, GCG DPP7 379/4885ALOX15 3799/4885MEN1 221/4885
US-20230071371-A1 PEPTIDE CONJUGATES AND METHODS OF USE GIPR, GLP1R, GRPR DPP7 148/4885ALOX15 3237/4885MEN1 328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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