Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | IL6 | P05231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732749 | 1.00 | TLR7 (0.48) | TLR7MEN1KMT2ANCF1PARP1 | |
| SCHEMBL24732576 | 0.91 | TLR7 (0.51) | TLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL29809227 | 0.91 | TLR7 (0.51) | TLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL29808892 | 0.90 | TLR7 (0.50) | TLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL24732757 | 0.90 | TLR7 (0.50) | TLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL24732732 | 0.89 | TLR7 (0.50) | TLR7 | |
| SCHEMBL29808991 | 0.89 | TLR7 (0.50) | TLR7 | |
| SCHEMBL24733037 | 0.88 | MEN1 (0.48) | MEN1KMT2ANCF1PARP1ALDH1A1 | |
| SCHEMBL24732752 | 0.88 | TLR7 (0.51) | TLR7IL6 | |
| SCHEMBL29809183 | 0.88 | MEN1 (0.48) | MEN1KMT2ANCF1PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |