Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24733037 | 1.00 | MEN1 (0.48) | MEN1KMT2APARP1NCF1POLB | |
| SCHEMBL24732778 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29809343 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29809002 | 0.90 | MAOB (0.43) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL24732724 | 0.90 | MAOB (0.43) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL24732749 | 0.88 | TLR7 (0.48) | MEN1KMT2APARP1NCF1ALDH1A1 | |
| SCHEMBL29809234 | 0.88 | MC4R (0.45) | PARP1NCF1ALDH1A1HTTHSD17B10 | |
| SCHEMBL24733475 | 0.88 | MC4R (0.45) | PARP1NCF1ALDH1A1HTTHSD17B10 | |
| SCHEMBL29808993 | 0.88 | TLR7 (0.48) | MEN1KMT2APARP1NCF1ALDH1A1 | |
| SCHEMBL28802656 | 0.87 | ADORA2A (0.44) | MEN1KMT2APARP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |