Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563335 | 1.00 | APP (0.79) | APPCYP1A2MAOBMAOANPC1 | |
| SCHEMBL1093700 | 0.91 | APP (0.67) | APPCYP1A2MAOBMAOANPC1 | |
| SCHEMBL19627050 | 0.89 | APP (0.78) | APPCYP1A2MAOBMAOAACHE | |
| SCHEMBL1104921 | 0.88 | APP (1.00) | APPCYP1A2NPC1MEN1KMT2A | |
| SCHEMBL18467806 | 0.88 | APP (0.80) | APPCYP1A2MAOBMAOANPC1 | |
| SCHEMBL10167879 | 0.88 | APP (0.80) | APPCYP1A2MAOBMAOANPC1 | |
| SCHEMBL19627047 | 0.88 | APP (0.70) | APPCYP1A2 | |
| SCHEMBL10167864 | 0.87 | APP (1.00) | APPCYP1A2MAOBMAOANPC1 | |
| SCHEMBL23623803 | 0.85 | APP (0.78) | APPCYP1A2MAOBMAOANPC1 | |
| SCHEMBL19630615 | 0.85 | APP (0.75) | APPCYP1A2MAOBMAOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741760-B1 | COMPOUNDS, PROCESS FOR OBTAINING THE COMPOUNDS, PHARMACEUTICAL COMPOSITION, USE OF THE COMPOUNDS AND METHOD FOR TREATING PSYCHIATRIC DISORDERS AND/OR SLEEP DISORDERS | ACHE LABORATORIOS FARMACEUTICOS SA (BR) | 2024-12-04 | — | — | EP | disclosed |
| CN-118525105-A | High ATP affinity proteins and inhibitors thereof as targets for treatment of refractory molecular subtype cancers | 维拉沃斯公司 | 2024-08-20 | — | — | CN | disclosed |
| US-11945864-B2 | Monoclonal antibody specifically binding to LAG-3 and use thereof | Y-Biologics Inc. (KR) | 2024-04-02 | — | — | US | disclosed |
| EP-3529234-B1 | COMPOUNDS, PROCESS FOR OBTAINING THE COMPOUNDS, PHARMACEUTICAL COMPOSITION, USE OF THE COMPOUNDS AND METHOD FOR TREATING PSYCHIATRIC DISORDERS AND/OR SLEEP DISORDERS | ACHE LABORATORIOS FARMACEUTICOS SA (BR) | 2023-11-29 | — | — | EP | disclosed |
| EP-4132975-A1 | MONOCLONAL ANTIBODIES AND ANTIGEN BINDING FRAGMENTS THEREOF FOR SUPPRESSING CD73 IMMUNE CHECKPOINT AND USES THEREOF | Aprilbio Co., Ltd (KR) | 2023-02-15 | — | — | EP | disclosed |
| CN-115181108-A | Compound and preparation method, pharmaceutical composition and application thereof | 艾奇实验室制药有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-110088092-B | Compounds, processes for their preparation, pharmaceutical compositions, uses of compounds and methods for treating psychiatric and/or sleep disorders | 艾奇实验室制药有限公司 | 2022-10-04 | — | — | CN | disclosed |