Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732755 | 1.00 | NLRP3 (0.52) | NLRP3TLR7L3MBTL1KCNH2TLR8 | |
| SCHEMBL24732627 | 0.89 | KCNH2 (0.46) | NLRP3TLR7L3MBTL1KCNH2 | |
| SCHEMBL29808996 | 0.89 | KCNH2 (0.46) | NLRP3TLR7L3MBTL1KCNH2 | |
| SCHEMBL29809227 | 0.86 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL24732576 | 0.86 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL24732757 | 0.85 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL29808892 | 0.85 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL24732732 | 0.82 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL24732616 | 0.82 | TLR7 (0.55) | TLR7 | |
| SCHEMBL29808991 | 0.82 | TLR7 (0.50) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |