SCHEMBL29809175

SCHEMBL29809175

N#CC(N)Cc1ccc(Br)cc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.41
DPP4 P27487 2/20 0.39
NAAA Q02083 1/20 0.35
DGAT1 O75907 1/20 0.35
CHRM5 P08912 1/20 0.35
KDM1A O60341 3/20 0.34
TRAP1 Q12931 3/20 0.34
HSP90B1 P14625 2/20 0.34
AKT1 P31749 1/20 0.34
KDM1B Q8NB78 1/20 0.33
PDPK1 O15530 1/20 0.33
AKR1B1 P15121 1/20 0.33
FAP Q12884 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16064312 1.00 PYCR1 (0.41) PYCR1DPP4NAAADGAT1CHRM5
SCHEMBL16043165 1.00 PYCR1 (0.41) PYCR1DPP4NAAADGAT1CHRM5
Hydrochloric Acid SCHEMBL31325365 0.98 PYCR1 (0.40) PYCR1DPP4NAAADGAT1CHRM5
Tartaric Acid SCHEMBL31325368 0.88 PDPK1 (0.38) PYCR1DPP4DGAT1PDPK1AKR1B1
SCHEMBL17713492 0.84 PYCR1 (0.39) PYCR1DPP4NAAADGAT1KDM1A
SCHEMBL4657227 0.83 PYCR1 (0.43) PYCR1DPP4NAAADGAT1CHRM5
SCHEMBL2928553 0.83 IDO1 (0.46) DPP4FAPDPP8DPP9DPP7
SCHEMBL16064343 0.80 PYCR1 (0.41) PYCR1DPP4FAPDPP8DPP9
SCHEMBL17483507 0.80 DPP4 (0.35) DPP4TRAP1HSP90B1FAPDPP8
SCHEMBL3761661 0.80 FFAR1 (0.38) DPP4DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108707140-B Protease C inhibitors 勃林格殷格翰国际有限公司 2022-07-22 CN disclosed