Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.57 |
| ▸ | NNMT | P40261 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22159524 | 1.00 | CRBN (0.57) | CRBNNNMTSMYD3 | |
| SCHEMBL5893559 | 0.85 | ABL1 (0.58) | CRBNNNMTSMYD3 | |
| SCHEMBL25311098 | 0.82 | CRBN (0.52) | CRBNNNMTSMYD3 | |
| SCHEMBL1094270 | 0.82 | CRBN (0.49) | CRBN | |
| SCHEMBL1094273 | 0.82 | CRBN (0.49) | CRBN | |
| SCHEMBL6244173 | 0.82 | CRBN (0.49) | CRBN | |
| Hydrochloric Acid SCHEMBL1092629 | 0.81 | CRBN (0.48) | CRBN | |
| Hydrochloric Acid SCHEMBL1092625 | 0.81 | CRBN (0.48) | CRBN | |
| SCHEMBL13925892 | 0.79 | CRBN (0.49) | CRBNNNMT | |
| SCHEMBL1093554 | 0.79 | CRBN (0.47) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278816-B | Dihydro quinolinones | C4医药公司 | 2024-03-15 | — | — | CN | disclosed |
| US-11401256-B2 | Dihydroquinolinones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401256-B2 | Dihydroquinolinones for medical treatment | CRBN, RBX1, ADRM1 | CRBN 1/4885NNMT 528/4885SMYD3 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.