Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 8/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21203057 | 1.00 | HTT (0.41) | HTTADRB2HSP90AA1ESR2TDP1 | |
| SCHEMBL30480768 | 0.84 | HSP90AA1 (0.40) | HTTADRB2HSP90AA1ESR2TDP1 | |
| SCHEMBL29105517 | 0.83 | TDP1 (0.55) | HTTHSP90AA1ESR2TDP1DHODH | |
| SCHEMBL30645299 | 0.83 | TDP1 (0.55) | HTTHSP90AA1ESR2TDP1DHODH | |
| SCHEMBL24963453 | 0.81 | HSP90AA1 (0.38) | HTTADRB2HSP90AA1ESR2TDP1 | |
| SCHEMBL4633149 | 0.80 | LMNA (0.43) | HTTHSP90AA1ESR2TDP1DHODH | |
| SCHEMBL31513744 | 0.80 | HSP90AA1 (0.38) | HTTADRB2HSP90AA1ESR2TDP1 | |
| SCHEMBL31513742 | 0.77 | MAPT (0.41) | HTTHSP90AA1ESR2TDP1DHODH | |
| SCHEMBL21783726 | 0.76 | POLB (0.39) | HSP90AA1ESR2TDP1PARP1KDM4E | |
| SCHEMBL4633001 | 0.74 | HSP90AA1 (0.38) | HTTHSP90AA1ESR2TDP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354889-B | Process for preparing benzimidazole derivatives | 怡诺安有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116354889-A | Process for preparing benzimidazole derivatives | 怡诺安有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-115594639-A | Synthesis method of key intermediate of Tegolrazan | 深圳市华先医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115108994-A | Tegolrazan intermediate and preparation method and application thereof | 江苏威奇达药业有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114805317-A | Preparation method of Tegolrazan | 江苏威奇达药业有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805317-A | Preparation method of Tegolrazan | 江苏威奇达药业有限公司 | 2022-07-29 | — | — | CN | disclosed |