Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 16/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29810123 | 0.99 | TPH1 (0.86) | TPH1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29810055 | 0.92 | TPH1 (1.00) | TPH1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29810078 | 0.92 | TPH1 (0.86) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810151 | 0.91 | TPH1 (0.86) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810109 | 0.91 | TPH1 (1.00) | TPH1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29810069 | 0.85 | TPH1 (1.00) | TPH1 | |
| SCHEMBL29810066 | 0.85 | TPH1 (1.00) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810122 | 0.85 | TPH1 (1.00) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810166 | 0.84 | TPH1 (1.00) | TPH1 | |
| SCHEMBL29810062 | 0.83 | TPH1 (0.83) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |