Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 19/20 | 0.78 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29810137 | 0.99 | TPH1 (0.78) | TPH1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL20777117 | 0.90 | TPH1 (0.81) | TPH1 | |
| SCHEMBL20777116 | 0.90 | TPH1 (0.81) | TPH1 | |
| Hydrochloric Acid SCHEMBL22150784 | 0.89 | TPH1 (0.82) | TPH1 | |
| SCHEMBL29810081 | 0.89 | TPH1 (0.80) | TPH1 | |
| SCHEMBL29810095 | 0.89 | TPH1 (0.80) | TPH1S1PR4S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL22150783 | 0.89 | TPH1 (0.82) | TPH1 | |
| SCHEMBL29810093 | 0.89 | TPH1 (0.80) | TPH1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL20777207 | 0.88 | TPH1 (1.00) | TPH1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL20777208 | 0.88 | TPH1 (1.00) | TPH1S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |