Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298109 | 1.00 | HCAR2 (0.42) | HCAR2AKR1B1GPR84PPARGPPARD | |
| SCHEMBL128174 | 0.88 | HCAR2 (0.53) | HCAR2 | |
| SCHEMBL158234 | 0.88 | AKR1B1 (0.53) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL1301122 | 0.88 | HCAR2 (0.53) | HCAR2 | |
| Adipic Acid SCHEMBL22444199 | 0.88 | AKR1B1 (0.53) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL128175 | 0.88 | HCAR2 (0.53) | HCAR2 | |
| SCHEMBL19471289 | 0.86 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL182514 | 0.86 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL5701165 | 0.86 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL30807881 | 0.86 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230414512-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. | 2023-12-28 | — | — | US | disclosed |
| EP-4218718-A2 | DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME | Laboratory Skin Care, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-2427178-B1 | DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME | LABORATORY SKIN CARE INC (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20210220276-A1 | Methods of Treating Skin | LABORATORY SKIN CARE, INC. | 2021-07-22 | — | — | US | disclosed |
| US-20200138718-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. | 2020-05-07 | — | — | US | disclosed |
| US-10350168-B2 | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same | LABORATORY SKIN CARE, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20170340566-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. | 2017-11-30 | — | — | US | disclosed |
| US-9707177-B2 | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same | LABORATORY SKIN CARE, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150004232-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. (US) | 2015-01-01 | — | — | US | disclosed |
| US-20130309276-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. (US) | 2013-11-21 | — | — | US | disclosed |
| US-8445002-B2 | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same | LABORATORY SKIN CARE, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| EP-2427178-A2 | DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME | Laboratory Skin Care, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20110189239-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. | 2011-08-04 | — | — | US | disclosed |
| WO-2010129819-A2 | DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME | LABORATORY SKIN CARE, INC. (US) | 2010-11-11 | — | — | WO | disclosed |