Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.39 |
| ▸ | MET | P08581 | 14/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23146988 | 1.00 | AXL (0.39) | AXLMETPDGFRAPSMD14KDR | |
| SCHEMBL23147141 | 0.84 | AXL (0.38) | AXLMETPDGFRAKDRMST1R | |
| SCHEMBL29812024 | 0.84 | AXL (0.38) | AXLMETPDGFRAKDRMST1R | |
| SCHEMBL30616271 | 0.83 | MET (0.52) | AXLMETPDGFRAKDRKIT | |
| SCHEMBL21200641 | 0.83 | MET (0.52) | AXLMETPDGFRAKDRKIT | |
| SCHEMBL23147081 | 0.81 | AXL (0.44) | AXLMETPDGFRAKDRKIT | |
| SCHEMBL29812553 | 0.81 | AXL (0.44) | AXLMETPDGFRAKDRKIT | |
| SCHEMBL23146659 | 0.80 | AXL (0.39) | AXLMETPDGFRAKDRKIT | |
| SCHEMBL29812312 | 0.80 | AXL (0.39) | AXLMETPDGFRAKDRKIT | |
| SCHEMBL23146736 | 0.80 | AXL (0.40) | AXLMETPDGFRAKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787144-A | Pyridone compounds and methods for modulating protein kinases | 埃克塞里艾克西斯公司 | 2022-07-22 | — | — | CN | disclosed |