Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761178 | 1.00 | POLB (0.57) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL11460466 | 0.86 | KDM4E (0.55) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL30995141 | 0.85 | KDM4E (0.50) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL23148030 | 0.85 | KDM4E (0.50) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL23147929 | 0.85 | KDM4E (0.54) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL23049623 | 0.85 | ALOX15 (0.55) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL29813118 | 0.85 | KDM4E (0.54) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL17429441 | 0.85 | KDM4E (0.54) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL23148112 | 0.84 | KDM4E (0.50) | POLBKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL29813123 | 0.84 | KDM4E (0.50) | POLBKDM4ERAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034103-A1 | INDOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |