Phosphoric Acid

Phosphoric Acid

SCHEMBL298141

O=P([O-])(O)O.O=P([O-])([O-])[O-].[Ca+2].[Ca+2]

nearest known ligand 0.73

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.73
LMNA P02545 3/20 0.40
KDM4E B2RXH2 2/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 1/20 0.39
TYMS P04818 1/20 0.38
FDPS P14324 3/20 0.35
BLM P54132 2/20 0.33
MMP2 P08253 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDE3A Q14432 1/20 0.30
CA1 P00915 2/20 0.30
CA4 P22748 2/20 0.30
CA5A P35218 2/20 0.30
CA5B Q9Y2D0 2/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28585359 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL28233830 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL2549258 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL29828900 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL7163381 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL8508247 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL11867838 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL3850640 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL39459 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL18887598 0.95 SLC34A1 (0.67) SLC34A1LMNAKDM4ECYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4491570-B1 PROCESS FOR THE PRODUCTION OF PHOSPHORUS OXICHLORIDE FROM MATERIAL CONTAINING PHOSPHORUS-OXYGEN COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2025-12-17 EP claimed
US-20200138718-A1 Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same LABORATORY SKIN CARE, INC. 2020-05-07 US claimed
CN-110075069-A Include activating agent-calcium phosphate granules compound dermal delivery composition and its application 实验室护肤股份有限公司 2019-08-02 CN claimed
CN-105311680-B A kind of preparation method of calcium phosphate bone cement that is while discharging zinc ion and silicate ion 华南理工大学 2018-10-09 CN claimed
US-20170340566-A1 Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same LABORATORY SKIN CARE, INC. 2017-11-30 US claimed
CN-105311680-A Preparation method of calcium phosphate bone cement simultaneously releasing zinc ions and silicate ions UNIV SOUTH CHINA TECH 2016-02-10 CN claimed
CN-104591793-B A kind of colored Pengyang china stone and preparation method thereof ZIBO DAYUNFANG COLORFUL PORCELAIN RESEARCH INSTITUTE (CN) 2016-01-20 CN claimed
CN-104591793-A Colored high-class daily delicate porcelain and preparation method thereof ZIBO DAYUNFANG COLORFUL PORCELAIN RES INST 2015-05-06 CN claimed
US-20150004232-A1 Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same LABORATORY SKIN CARE, INC. (US) 2015-01-01 US claimed
CN-103060479-B Method for cleaning sugar preparing and boiling materials GUANGXI LIUZHOU ZHONGJIA INTELLECTUAL PROPERTY RIGHTS SERVICE CO LTD 2014-05-28 CN claimed
CN-101530630-B X-ray developable calcium phosphate bone cement and preparation method and application thereof UNIV SOUTH CHINA TECH 2012-05-30 CN claimed
EP-2427178-A2 DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME Laboratory Skin Care, Inc. (US) 2012-03-14 EP claimed
US-20110189239-A1 Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same LABORATORY SKIN CARE, INC. 2011-08-04 US claimed
CN-101337080-B Radionuclide particle implantation medicine for cancer, use and preparation method thereof UNIV SOUTHEAST 2010-12-08 CN claimed
WO-2010129819-A2 DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME LABORATORY SKIN CARE, INC. (US) 2010-11-11 WO claimed
CN-100546661-C A kind of preparation method of in situ pore-forming self-setting calcium phosphate composite tissue engineering scaffold UNIV SOUTH CHINA TECH (CN) 2009-10-07 CN claimed
CN-101530630-A X-ray developing calcium phosphate cement and preparation method and application thereof UNIV SOUTH CHINA TECH 2009-09-16 CN claimed
CN-101461963-A Multiplex composite bone tissue engineering bracket material capable of degrading gradiently and preparation method thereof UNIV SOUTH CHINA TECH (CN) 2009-06-24 CN claimed
CN-101007183-A Preparation method of an in situ pore-forming self-setting calcium phosphate composite tissue engineering scaffold UNIV SOUTH CHINA TECH (CN) 2007-08-01 CN claimed
CN-1184454-A Bone substitute material and method for producing the same ETEX CORP (US) 1998-06-10 CN claimed