SCHEMBL29816396

SCHEMBL29816396

Cn1nccc1-c1ccccc1Oc1ccc(S(=O)(=O)Nc2nccs2)cc1C#N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16530690 1.00 SCN9A (1.00) SCN9A
SCHEMBL16531049 0.93 SCN9A (1.00) SCN9A
SCHEMBL16530691 0.92 SCN9A (1.00) SCN9A
SCHEMBL16531246 0.92 SCN9A (1.00) SCN9A
SCHEMBL1690656 0.92 SCN9A (0.84) SCN9A
SCHEMBL16530575 0.91 SCN9A (1.00) SCN9A
SCHEMBL16531006 0.91 SCN9A (1.00) SCN9A
SCHEMBL16530820 0.90 SCN9A (1.00) SCN9A
SCHEMBL16531649 0.90 SCN9A (1.00) SCN9A
SCHEMBL322806 0.90 SCN9A (1.00) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106656-A1 METHODS OF PREVENTING OR REDUCING CARTILAGE LOSS AND/OR JOINT DAMAGE USING NAV 1.7 INHIBITORS YALE UNIVERSITY (US) 2025-05-22 WO claimed
US-12533309-B2 Minoxidil adjuvant therapies CARING BRANDS, INC. (US) 2026-01-27 US disclosed
US-12527729-B2 Minoxidil adjuvant therapies CARING BRANDS, INC. (US) 2026-01-20 US disclosed
US-20250360128-A1 MINOXIDIL ADJUVANT THERAPIES JUPITER WELLNESS INC (US) 2025-11-27 US disclosed
WO-2025106656-A1 METHODS OF PREVENTING OR REDUCING CARTILAGE LOSS AND/OR JOINT DAMAGE USING NAV 1.7 INHIBITORS YALE UNIVERSITY (US) 2025-05-22 WO disclosed
EP-4536354-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2025-04-16 EP disclosed
US-20240009101-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2024-01-11 US disclosed
US-20230404886-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2023-12-21 US disclosed
CN-117243839-A Minoxidil adjuvant therapy 应用生物学股份有限公司 2023-12-19 CN disclosed
US-11766392-B2 Minoxidil adjuvant therapies Jupiter Wellness, Inc. (US) 2023-09-26 US disclosed
CN-110088093-B Acyl sulfonamide nav1.7 inhibitors 百时美施贵宝公司 2023-06-13 CN disclosed
US-11628132-B2 Minoxidil adjuvant therapies Jupiter Wellness, Inc. (US) 2023-04-18 US disclosed
US-20220296486-A1 Minoxidil Adjuvant Therapies Jupiter Wellness, Inc. 2022-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527729-B2 Minoxidil adjuvant therapies RXRA, RXRB, RXRG SCN9A 1256/4885
US-12533309-B2 Minoxidil adjuvant therapies RXRG, RXRA, RXRB SCN9A 2659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.