Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 4/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | GNPAT | O15228 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8526715 | 0.92 | NPY4R (0.48) | NPY4RALBSIRT6SIRT1SIRT5 | |
| SCHEMBL6026003 | 0.92 | FOLH1 (0.49) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| SCHEMBL446929 | 0.92 | FOLH1 (0.49) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| SCHEMBL468901 | 0.92 | FOLH1 (0.49) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| SCHEMBL30526285 | 0.92 | FOLH1 (0.49) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| Water SCHEMBL29401510 | 0.90 | FOLH1 (0.48) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| Acetic Acid SCHEMBL28406175 | 0.90 | FOLH1 (0.48) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| Hydrochloric Acid SCHEMBL4422480 | 0.90 | FOLH1 (0.48) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| SCHEMBL9438405 | 0.90 | FOLH1 (0.48) | NPY4RFOLH1GNPATSMN1; SMN2ALB | |
| SCHEMBL468736 | 0.87 | FOLH1 (0.55) | FOLH1GNPATSMN1; SMN2ALBSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779090-B | 2-ring heterocyclic compound | 住友制药株式会社 | 2022-07-26 | — | — | CN | disclosed |