SCHEMBL446929

SCHEMBL446929

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nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.49
GNPAT O15228 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
NFKB1 P19838 1/20 0.44
PTGS2 P35354 1/20 0.44
THPO P40225 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
ALB P02768 3/20 0.44
SIRT6 Q8N6T7 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
ALDH1A1 P00352 1/20 0.43
SIRT5 Q9NXA8 3/20 0.42
C3AR1 Q16581 1/20 0.40
NOD1 Q9Y239 2/20 0.39
CHRM2 P08172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026003 1.00 FOLH1 (0.49) FOLH1GNPATSMN1; SMN2KDM4EMAPT
SCHEMBL30526285 1.00 FOLH1 (0.49) FOLH1GNPATSMN1; SMN2KDM4EMAPT
SCHEMBL468901 1.00 FOLH1 (0.49) FOLH1GNPATSMN1; SMN2KDM4EMAPT
Acetic Acid SCHEMBL28406175 0.98 FOLH1 (0.48) FOLH1GNPATSMN1; SMN2KDM4EMAPT
SCHEMBL9438405 0.98 FOLH1 (0.48) FOLH1GNPATSMN1; SMN2KDM4EMAPT
Water SCHEMBL29401510 0.98 FOLH1 (0.48) FOLH1GNPATSMN1; SMN2KDM4EMAPT
Hydrochloric Acid SCHEMBL4422480 0.98 FOLH1 (0.48) FOLH1GNPATSMN1; SMN2KDM4EMAPT
SCHEMBL468736 0.95 FOLH1 (0.55) FOLH1GNPATSMN1; SMN2KDM4EMAPT
SCHEMBL22769501 0.95 FOLH1 (0.55) FOLH1GNPATSMN1; SMN2KDM4EMAPT
SCHEMBL29550463 0.95 FOLH1 (0.55) FOLH1GNPATSMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011156-A Weight-losing peptide with high activity and preparation method and application thereof 济南健丰化工有限公司 2026-05-12 CN claimed
EP-4731755-A2 COMPOSITIONS AND METHODS FOR REDUCING HOST CELL PROTEINS IN RECOMBINANT ADENO-ASSOCIATED VIRUS PREPARATIONS Ultragenyx Pharmaceutical Inc. (US) 2026-04-29 EP claimed
US-12599669-B2 Use of low molecular weight polyvinylpyrrolidone (PVP) to reduce viscosity of high concentration protein formulations AMGEN INC. (US) 2026-04-14 US claimed
US-20260049105-A1 SELECTIVE MC4R LIGAND FOR TREATING OBESITY AND COGNITIVE LOSS UNIV ARIZONA (US) 2026-02-19 US claimed
US-20250367115-A1 Excipients To Reduce the Viscosity of Antibody Formulations and Formulation Compositions AMGEN INC. (US) 2025-12-04 US claimed
WO-2025245279-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONISTS AND USE THEREFORE IN TREATMENT OF ADDICTION AND/OR PAIN ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2025245258-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONIST ANALOGS FOR MODULATING WEIGHT GAIN ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2025245294-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONISTS AND USES THEREOF FOR MODULATING WEIGHT GAIN ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2025245244-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONIST ANALOGS FOR MODULATING WEIGHT LOSS ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2025245252-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONIST ANALOGS FOR USE IN PAIN MANAGEMENT AND/OR SUBSTANCE USE DISORDERS ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
EP-0754023-B1 INHIBITION OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1999-05-26 EP claimed
EP-0673432-B1 PROCESS FOR PREPARING CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 1999-03-24 EP claimed
US-5869299-A USING AN ENZYME SYSTEM FROM STREPTOMYCES, PARTICULARLY S. CLAVULIGERUS. SMITHKLINE BEECHAM P.L.C. (GB) 1999-02-09 US claimed
US-5686416-A BRADYKININ ANALOGUES; NONA-, DECA- AND POLYPEPTIDES ALKERMES, INC. (US) 1997-11-11 US claimed
EP-0736770-A2 An immunoreactive conjugate, method for its preparation, antibodies to said conjugate and a pharmaceutical composition and diagnostic device containing them ANDA BIOLOGICALS S.A. (FR) 1996-10-09 EP claimed
US-5468476-A Enzyme inhibitor GILLETTE CO., THE 1995-11-21 US claimed
EP-0673432-A1 PROCESS FOR PREPARING CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 1995-09-27 EP claimed
US-5350766-A Method for the prevention and/or palliation of the complications of diabetes using N-alpha orginine acetyl NEW YORK MEDICAL COLLEGE (US) 1994-09-27 US claimed
WO-1994012654-A1 PROCESS FOR PREPARING CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 1994-06-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049105-A1 SELECTIVE MC4R LIGAND FOR TREATING OBESITY AND COGNITIVE LOSS MC4R, MC3R, NPY4R FOLH1 2873/4885GNPAT 2101/4885SMN1; SMN2 3094/4885
US-20250367115-A1 Excipients To Reduce the Viscosity of Antibody Formulations and Formulation Compositions ARGLU1, ARG1, FCGRT FOLH1 405/4885GNPAT 4113/4885SMN1; SMN2 3271/4885
US-12599669-B2 Use of low molecular weight polyvinylpyrrolidone (PVP) to reduce viscosity of high concentration protein formulations PNISR, ALB, ACP1 FOLH1 2031/4885GNPAT 3020/4885SMN1; SMN2 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.