Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21404824 | 0.94 | MDM2 (0.54) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL18795317 | 0.94 | MDM2 (0.54) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL29401864 | 0.90 | MDM4 (0.55) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL19899314 | 0.90 | MDM4 (0.55) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL30191422 | 0.90 | MDM4 (0.55) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL31165326 | 0.90 | MDM4 (0.55) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL31000735 | 0.90 | MDM4 (0.55) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL13611972 | 0.90 | MDM4 (0.55) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL20546469 | 0.89 | MDM4 (0.53) | MDM4TP53MDM2TLR2CASP3 | |
| SCHEMBL17981392 | 0.89 | MDM4 (0.53) | MDM4TP53MDM2TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337791-B1 | INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF | UNIV HEALTH NETWORK (CA) | 2022-08-03 | — | — | EP | disclosed |