Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27156523 | 1.00 | CSNK1A1 (0.30) | CSNK1A1CLK4 | |
| SCHEMBL18366264 | 0.77 | CDK1 (0.40) | — | |
| SCHEMBL24267915 | 0.70 | ADORA3 (0.32) | — | |
| SCHEMBL29390081 | 0.70 | ADORA3 (0.32) | — | |
| SCHEMBL27156683 | 0.67 | CA12 (0.30) | — | |
| SCHEMBL27156681 | 0.67 | CA12 (0.30) | — | |
| SCHEMBL29819875 | 0.67 | CA12 (0.30) | — | |
| SCHEMBL29636852 | 0.65 | PDE2A (0.47) | — | |
| SCHEMBL13087506 | 0.65 | PDE2A (0.47) | — | |
| SCHEMBL30587629 | 0.64 | AURKA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022197641-A1 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-YL-AMINE DERIVATIVES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) MODULATORS AND/OR INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | RAPT THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |