Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 18/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.34 |
| ▸ | BIRC8 | Q96P09 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341283 | 1.00 | XIAP (0.35) | XIAPTACR1BIRC3BIRC2BIRC8 | |
| SCHEMBL24665652 | 1.00 | XIAP (0.35) | XIAPTACR1BIRC3BIRC2BIRC8 | |
| SCHEMBL29230882 | 1.00 | XIAP (0.35) | XIAPTACR1BIRC3BIRC2BIRC8 | |
| SCHEMBL29231053 | 0.89 | XIAP (0.34) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL26816159 | 0.89 | XIAP (0.34) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL24666001 | 0.89 | CNR1 (0.32) | XIAPTACR1BIRC3BIRC2BIRC8 | |
| SCHEMBL29230802 | 0.89 | CNR1 (0.32) | XIAPTACR1BIRC3BIRC2BIRC8 | |
| SCHEMBL24665653 | 0.88 | CNR1 (0.32) | XIAPTACR1BIRC3BIRC2BIRC8 | |
| SCHEMBL30341395 | 0.88 | CFD (0.36) | — | |
| SCHEMBL29820563 | 0.88 | CFD (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308095-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022198196-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |