Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.47 |
| ▸ | THRB | P10828 | 14/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168655 | 1.00 | THRA (0.47) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL23168930 | 0.93 | THRA (0.51) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL23168723 | 0.91 | THRA (0.50) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL23168776 | 0.88 | THRA (0.51) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL29822030 | 0.88 | THRA (0.46) | THRATHRBCYP2C8CYP2C9L3MBTL1 | |
| SCHEMBL23168737 | 0.88 | THRA (0.46) | THRATHRBCYP2C8CYP2C9L3MBTL1 | |
| SCHEMBL23168929 | 0.87 | THRA (0.49) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL23168754 | 0.86 | THRA (0.49) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL23152134 | 0.85 | THRA (0.47) | THRATHRBCYP2C8CYP2C9MAPT | |
| SCHEMBL24819240 | 0.84 | THRA (0.48) | THRATHRBCYP2C8CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4036090-A1 | CHEMICAL COMPOUND AS THYROID HORMONE BETA RECEPTOR AGONIST AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-08-03 | — | — | EP | disclosed |