Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.55 |
| ▸ | ESR1 | P03372 | 6/20 | 0.55 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
| ▸ | WIZ | O95785 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23117841 | 1.00 | CRBN (0.55) | CRBNESR1IKZF2IKZF3WIZ | |
| SCHEMBL23117840 | 1.00 | CRBN (0.55) | CRBNESR1IKZF2IKZF3WIZ | |
| SCHEMBL30985054 | 0.91 | CRBN (0.62) | CRBNESR1IKZF2WIZDDB1 | |
| SCHEMBL29821891 | 0.89 | CRBN (0.57) | CRBNESR1IKZF2IKZF3WIZ | |
| SCHEMBL23117831 | 0.89 | CRBN (0.57) | CRBNESR1IKZF2IKZF3WIZ | |
| SCHEMBL23117830 | 0.89 | CRBN (0.57) | CRBNESR1IKZF2IKZF3WIZ | |
| SCHEMBL29822127 | 0.87 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL23117907 | 0.87 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL22661387 | 0.87 | CRBN (0.58) | CRBNESR1IKZF2IKZF3WIZ | |
| SCHEMBL29596744 | 0.86 | CRBN (0.56) | CRBNESR1IKZF2IKZF3WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034114-A1 | NOVEL UREAS HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. (US) | 2022-08-03 | — | — | EP | disclosed |