Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.49 |
| ▸ | PLK4 | O00444 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23117907 | 1.00 | CRBN (0.57) | CRBNDDB1ARBTKPLK4 | |
| SCHEMBL29821993 | 0.93 | CRBN (0.54) | CRBNDDB1ARBTKEGFR | |
| SCHEMBL23117865 | 0.93 | CRBN (0.54) | CRBNDDB1ARBTKEGFR | |
| SCHEMBL25690999 | 0.93 | CRBN (0.66) | CRBNDDB1BTKMEN1KMT2A | |
| SCHEMBL25691416 | 0.92 | CRBN (0.47) | CRBNDDB1ARBTKPLK4 | |
| SCHEMBL23117832 | 0.91 | CRBN (0.57) | CRBNDDB1ARBTKPLK4 | |
| SCHEMBL23117898 | 0.88 | CRBN (0.58) | CRBNDDB1ARBTKPLK4 | |
| SCHEMBL29822185 | 0.88 | CRBN (0.58) | CRBNDDB1ARBTKPLK4 | |
| SCHEMBL25691074 | 0.88 | CRBN (0.54) | CRBNDDB1ARBTKPLK4 | |
| SCHEMBL29821966 | 0.87 | CRBN (0.55) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034114-A1 | NOVEL UREAS HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. (US) | 2022-08-03 | — | — | EP | disclosed |