SCHEMBL5357863

SCHEMBL5357863

O=C(O)c1ccc(Nc2cccc3ncccc23)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 4/20 0.61
DNMT3A Q9Y6K1 3/20 0.61
HDAC6 Q9UBN7 3/20 0.61
HDAC3 O15379 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
HDAC5 Q9UQL6 2/20 0.61
ACHE P22303 1/20 0.61
DNMT3L Q9UJW3 1/20 0.61
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
PABPC1 P11940 2/20 0.54
EIF4H Q15056 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPKAPK2 P49137 1/20 0.54
ATM Q13315 1/20 0.54
ALDH1A1 P00352 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29822716 0.90 DNMT1 (0.75) DNMT1DNMT3AHDAC6HDAC3HDAC1
SCHEMBL1891738 0.90 DNMT1 (0.75) DNMT1DNMT3AHDAC6HDAC3HDAC1
Hydrochloric Acid SCHEMBL1887938 0.89 DNMT1 (0.73) DNMT1DNMT3AHDAC6HDAC3HDAC1
SCHEMBL19039688 0.86 CDC25B (0.63) DNMT1DNMT3AMEN1KMT2AL3MBTL1
SCHEMBL5377149 0.85 KDM4E (0.59) DNMT1DNMT3AHDAC6HDAC3HDAC1
SCHEMBL17194814 0.83 MEN1 (0.62) DNMT1DNMT3AHDAC6HDAC3HDAC1
SCHEMBL23627522 0.81 ALK (0.60) DNMT1DNMT3AHDAC6HDAC3HDAC1
SCHEMBL21264424 0.79 ADRA2A (0.58) DNMT1DNMT3AHDAC6HDAC3HDAC1
SCHEMBL19631407 0.78 HDAC6 (0.75) HDAC6HDAC3HDAC1HDAC2MEN1
Terephthalic Acid SCHEMBL1649598 0.78 MAPT (0.64) HDAC6MEN1KMT2APABPC1EIF4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7238228-B2 Magenta metal chelate dyes and their use in ink-jet printers FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-07-03 US disclosed
US-20060180050-A1 Magenta metal chelate dyes and their use in ink-jet printers FUJIFILM IMAGING COLORANTS LIMITED (GB) 2006-08-17 US disclosed
WO-2004087814-A1 MAGENTA METAL CHELATE DYES AND THEIR USE IN INK-JET PRINTERS AVECIA INKJET LIMITED (GB) 2004-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060180050-A1 Magenta metal chelate dyes and their use in ink-jet printers IK, MARK1, IDH1 DNMT1 1284/4885DNMT3A 464/4885HDAC6 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.