Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12984443 | 0.86 | — | — | |
| SCHEMBL23743045 | 0.82 | — | — | |
| SCHEMBL17675657 | 0.82 | EPHX1 (0.38) | EPHX1EPHX2HCAR2 | |
| SCHEMBL20031997 | 0.80 | EPHX1 (0.37) | EPHX1EPHX2HCAR2 | |
| SCHEMBL20031998 | 0.80 | EPHX1 (0.37) | EPHX1EPHX2HCAR2 | |
| SCHEMBL5683395 | 0.80 | EPHX1 (0.37) | EPHX1EPHX2HCAR2 | |
| SCHEMBL20032245 | 0.80 | EPHX1 (0.37) | EPHX1EPHX2HCAR2 | |
| Ammonia Solution, Strong SCHEMBL27350163 | 0.80 | EPHX1 (0.37) | EPHX1EPHX2HCAR2 | |
| SCHEMBL135922 | 0.78 | EPHX1 (0.36) | EPHX1EPHX2HCAR2 | |
| SCHEMBL23921593 | 0.77 | SMYD3 (0.36) | EPHX1EPHX2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173895-A1 | IMIDAZOLOPYRIMIDINES AND IMIDAZOLOTRIAZINE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE(PARP) | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI (IT) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173895-A1 | IMIDAZOLOPYRIMIDINES AND IMIDAZOLOTRIAZINE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE(PARP) | PARP1, PARP2, PARP15 | EPHX1 3730/4885EPHX2 4312/4885HCAR2 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.