Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.37 |
| ▸ | CDC25B | P30305 | 6/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27054999 | 0.95 | SELP (0.37) | SELPCYP2D6ALDH1A1MAPK1PTPN1 | |
| SCHEMBL30829360 | 0.88 | SELP (0.41) | SELPCYP2D6ALDH1A1MAPK1PTPN1 | |
| SCHEMBL29827837 | 0.87 | SSTR1 (0.42) | SELPPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL29827728 | 0.86 | SELP (0.41) | SELPPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL31745725 | 0.86 | SELP (0.42) | SELPCYP2D6ALDH1A1MAPK1PTPN1 | |
| SCHEMBL29827581 | 0.85 | TNF (0.47) | SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL31745662 | 0.83 | SELP (0.42) | SELPPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL13925621 | 0.82 | SSTR1 (0.40) | SELPPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL27055012 | 0.82 | SELP (0.42) | SELPSSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL27054862 | 0.82 | SELP (0.37) | SELPSSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301374-A1 | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS | Deciduous Therapeutics, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187141-A1 | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS | DECIDUOUS THERAPEUTICS (US) | 2022-09-09 | — | — | WO | disclosed |