Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.47 |
| ▸ | SELP | P16109 | 5/20 | 0.37 |
| ▸ | TLR2 | O60603 | 6/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | CDC25B | P30305 | 3/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29827596 | 0.85 | SELP (0.39) | SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL30829360 | 0.81 | SELP (0.41) | TNFSELPPTPN1CDC25B | |
| SCHEMBL29827837 | 0.80 | SSTR1 (0.42) | SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL27054999 | 0.80 | SELP (0.37) | TNFSELPPTPN1CDC25B | |
| SCHEMBL29827728 | 0.79 | SELP (0.41) | SELPPTPN1CDC25B | |
| SCHEMBL31745725 | 0.79 | SELP (0.42) | SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL31745662 | 0.77 | SELP (0.42) | TNFSELPPTPN1CDC25BPTPN2 | |
| SCHEMBL13925621 | 0.76 | SSTR1 (0.40) | SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL27055012 | 0.76 | SELP (0.42) | SELP | |
| SCHEMBL29827765 | 0.75 | SLC10A2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301374-A1 | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS | Deciduous Therapeutics, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187141-A1 | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS | DECIDUOUS THERAPEUTICS (US) | 2022-09-09 | — | — | WO | disclosed |