Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | REN | P00797 | 1/20 | 0.60 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | BMP1 | P13497 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595064 | 0.94 | NMBR (0.74) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL5380441 | 0.94 | NMBR (0.74) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL11765479 | 0.92 | NMBR (0.71) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL14027229 | 0.92 | NMBR (0.71) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL16617130 | 0.92 | NMBR (0.71) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL5380023 | 0.92 | NMBR (0.71) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL11330243 | 0.91 | NMBR (0.70) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL17319524 | 0.90 | NMBR (0.73) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL1318661 | 0.90 | NMBR (0.73) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL29401413 | 0.90 | NMBR (0.73) | NMBRMAPTLMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108953-B | Sulfhydrylation of alkynylamides and selective modification of polypeptide cysteines | 江西师范大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-115108953-A | Thiohydrogenation of alkynylamides and selective modification of polypeptide cysteines | 江西师范大学 | 2022-09-27 | — | — | CN | disclosed |