SCHEMBL5380441

SCHEMBL5380441

COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NMBR P28336 4/20 0.74
MAPT P10636 2/20 0.73
LMNA P02545 1/20 0.73
GAA P10253 1/20 0.73
HTT P42858 1/20 0.73
TACR1 P25103 1/20 0.63
REN P00797 1/20 0.63
SIRT5 Q9NXA8 1/20 0.62
CA2 P00918 1/20 0.62
BMP1 P13497 1/20 0.61
MME P08473 2/20 0.60
ECE1 P42892 2/20 0.60
IL1RN P18510 1/20 0.60
ERAP2 Q6P179 1/20 0.60
ERAP1 Q9NZ08 1/20 0.60
CASP1 P29466 1/20 0.60
CASP3 P42574 1/20 0.60
CASP7 P55210 1/20 0.60
MMP2 P08253 1/20 0.60
MMP9 P14780 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14595064 1.00 NMBR (0.74) NMBRMAPTLMNAGAAHTT
SCHEMBL5380023 0.98 NMBR (0.71) NMBRMAPTLMNAGAAHTT
SCHEMBL14027229 0.98 NMBR (0.71) NMBRMAPTLMNAGAAHTT
SCHEMBL16617130 0.98 NMBR (0.71) NMBRMAPTLMNAGAAHTT
SCHEMBL11765479 0.98 NMBR (0.71) NMBRMAPTLMNAGAAHTT
SCHEMBL29401413 0.96 NMBR (0.73) NMBRMAPTLMNAGAAHTT
SCHEMBL17319524 0.96 NMBR (0.73) NMBRMAPTLMNAGAAHTT
SCHEMBL1318661 0.96 NMBR (0.73) NMBRMAPTLMNAGAAHTT
SCHEMBL11330243 0.95 NMBR (0.70) NMBRMAPTLMNAGAAHTT
SCHEMBL29828016 0.94 NMBR (0.69) NMBRMAPTLMNAGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024041532-A1 TETRAVALENT PLATINUM-CONTAINING COMPLEX, PRODRUG, PREPARATION METHOD THEREFOR, AND USE THEREOF 赣州和美药业股份有限公司 2024-02-29 WO disclosed
CN-117603299-A Tetravalent platinum-containing complex, prodrug, preparation method and application thereof 赣州和美药业股份有限公司 2024-02-27 CN disclosed
US-7163671-B2 Long-term stabilized formulations CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-01-16 US disclosed
US-20030092622-A1 Preparation stabilized over long time CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-05-15 US disclosed
EP-1260230-A1 PREPARATIONS STABILIZED OVER LONG TIME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-11-27 EP disclosed