Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805748 | 0.80 | HDAC3 (0.57) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL29828867 | 0.80 | HDAC3 (0.57) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL29828305 | 0.78 | MAPT (0.58) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL29828417 | 0.77 | MAPT (0.54) | MAPTRAB9AALDH1A1TSHRLMNA | |
| SCHEMBL9831966 | 0.73 | MAPT (0.48) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL29828275 | 0.72 | HDAC8 (0.57) | ALDH1A1LMNAHPGDHDAC3HDAC4 | |
| SCHEMBL29828407 | 0.70 | HPGD (0.65) | MAPTRAB9AALDH1A1KDM4ETSHR | |
| SCHEMBL11601130 | 0.70 | LMNA (0.59) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL1771059 | 0.67 | HPGD (0.60) | MAPTRAB9AALDH1A1KDM4ETSHR | |
| SCHEMBL23200035 | 0.67 | TSHR (0.53) | MAPTMEN1ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805108-B | Preparation method of chiral beta-alkylamide compound | 南方科技大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-114805108-A | Preparation method of chiral beta-alkyl amide compound | 南方科技大学 | 2022-07-29 | — | — | CN | disclosed |