SCHEMBL29828656

SCHEMBL29828656

CCO[C@H]1CN(C2CCC(O)(c3ccc4c(c3)OCO4)CC2)C[C@@H]1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 20/20 1.00
KCNH2 Q12809 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395517 1.00 CCR2 (1.00) CCR2KCNH2
SCHEMBL747726 1.00 CCR2 (1.00) CCR2KCNH2
SCHEMBL746351 0.95 CCR2 (0.90) CCR2KCNH2
SCHEMBL744288 0.89 CCR2 (0.89) CCR2KCNH2
SCHEMBL744287 0.89 CCR2 (0.89) CCR2KCNH2
SCHEMBL745716 0.89 CCR2 (1.00) CCR2KCNH2
SCHEMBL743857 0.89 CCR2 (0.84) CCR2KCNH2
SCHEMBL745717 0.89 CCR2 (1.00) CCR2KCNH2
SCHEMBL765257 0.89 CCR2 (1.00) CCR2KCNH2
SCHEMBL746250 0.89 CCR2 (1.00) CCR2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094689-A Combination therapy of diacylglycerol kinase (DGK) alpha inhibitors with other therapies 2026-05-26 CN claimed
US-20250171546-A1 DUPILUMAB FOR TREATMENT OF COVID-19 UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-05-29 US disclosed
CN-111247163-B Screening assays, modulators and modulators of progressive glycation end product Receptor (RAGE) activation 莫纳施大学 2024-11-26 CN disclosed
US-11771759-B2 Immunopotentiator, immunotherapeutic pharmaceutical composition and its preparation and use FUDAN UNIVERSITY (CN) 2023-10-03 US disclosed
WO-2023164655-A1 DUPILUMAB FOR TREATMENT OF COVID-19 UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2023-08-31 WO disclosed
US-20220175912-A1 IMMUNOPOTENTIATOR, IMMUNOTHERAPEUTIC PHARMACEUTICAL COMPOSITION AND ITS PREPARATION AND USE FUDAN UNIVERSITY (CN) 2022-06-09 US disclosed