Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.40 |
| ▸ | SGK1 | O00141 | 5/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596663 | 1.00 | CCR2 (0.44) | CCR2SLC40A1SGK1KITBRD4 | |
| SCHEMBL21596696 | 0.89 | CCR2 (0.43) | CCR2SLC40A1SGK1KITNR4A2 | |
| SCHEMBL29365104 | 0.89 | CCR2 (0.43) | CCR2SLC40A1SGK1KITNR4A2 | |
| SCHEMBL21596672 | 0.86 | SGK1 (0.42) | CCR2SLC40A1SGK1NR4A2 | |
| SCHEMBL29829666 | 0.86 | SGK1 (0.42) | CCR2SLC40A1SGK1NR4A2 | |
| SCHEMBL23610281 | 0.84 | SGK1 (0.46) | CCR2SLC40A1SGK1 | |
| SCHEMBL29830171 | 0.84 | SGK1 (0.46) | CCR2SLC40A1SGK1 | |
| SCHEMBL20355355 | 0.83 | CCR2 (0.46) | CCR2SLC40A1SGK1KITNR4A2 | |
| SCHEMBL30286604 | 0.83 | CCR2 (0.46) | CCR2SLC40A1SGK1KITNR4A2 | |
| SCHEMBL21596656 | 0.83 | SGK1 (0.40) | CCR2SLC40A1SGK1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |