Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | CRHBP | P24387 | 3/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | CDK8 | P49336 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386448 | 0.79 | MAPT (0.67) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL6068061 | 0.79 | MAPT (0.58) | MEN1MAPTKMT2AGAAKDM4E | |
| SCHEMBL9395569 | 0.77 | MAPT (0.72) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL2061095 | 0.77 | RECQL (0.58) | KMT2AGAATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3750282 | 0.76 | MEN1 (0.70) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL28427495 | 0.76 | MAPT (0.71) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL9395627 | 0.76 | MAPT (0.70) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL2059682 | 0.76 | MAPT (1.00) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL6815029 | 0.76 | KMT2A (0.70) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL12497079 | 0.76 | KDM4E (0.66) | MEN1KMT2ACRHBPCRHR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |