Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.70 |
| ▸ | CRHBP | P24387 | 3/20 | 0.70 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PTPRF | P10586 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395569 | 0.84 | MAPT (0.72) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL5374323 | 0.82 | KMT2A (0.54) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL28427495 | 0.82 | MAPT (0.71) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL2059682 | 0.82 | MAPT (1.00) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL6815029 | 0.82 | KMT2A (0.70) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL9395627 | 0.82 | MAPT (0.70) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL18610468 | 0.82 | PTPRF (0.62) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL16830254 | 0.82 | MAPT (0.55) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL4212246 | 0.80 | MAPT (1.00) | MEN1MAPTKMT2ACRHBPCRHR2 | |
| SCHEMBL27376900 | 0.80 | MAPT (0.67) | MEN1MAPTKMT2ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738169-B1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO LTD (CN) | 2016-03-23 | — | — | EP | disclosed |
| EP-2738169-B1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO LTD (CN) | 2016-03-23 | — | — | EP | disclosed |
| US-8946436-B2 | Oxazolidinone compounds and their uses in preparation of antibiotics | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| US-8946436-B2 | Oxazolidinone compounds and their uses in preparation of antibiotics | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| US-8946436-B2 | Oxazolidinone compounds and their uses in preparation of antibiotics | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| EP-2738169-A1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2014-06-04 | — | — | EP | disclosed |
| EP-2738169-A1 | OXAZOLIDINONE COMPOUNDS AND THEIR USES IN PREPARATION OF ANTIBIOTICS | SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD. (CN) | 2014-06-04 | — | — | EP | disclosed |
| US-20140142144-A1 | Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics | SI CHUAN UNIVERSITY (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20140142144-A1 | Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics | SI CHUAN UNIVERSITY (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20140142144-A1 | Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics | SI CHUAN UNIVERSITY (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-11-25 | — | — | US | disclosed |
| WO-2008143649-A2 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008143649-A2 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-11-27 | — | — | WO | disclosed |
| CN-1075073-C | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials | UPJOHN CO (US) | 2001-11-21 | — | — | CN | disclosed |
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5910504-A | BACTERICIDES TREATING INFECTIONS | PHARMACIA & UPJOHN (US) | 1999-06-08 | — | — | US | disclosed |
| CN-1172484-A | Phenyl oxazolidinone antibacterial agents substituted with heteroaromatic rings | UPJOHN CO (US) | 1998-02-04 | — | — | CN | disclosed |
| EP-0807112-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | OXA1L, MIF, VIP | MEN1 4412/4885MAPT 3957/4885KMT2A 4557/4885 |
| US-20140142144-A1 | Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics | OXA1L, ALPI, APC | MEN1 2230/4885MAPT 3516/4885KMT2A 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.