Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23195488 | 0.83 | IGF1R (0.41) | CTSVCTSLKMT2AMEN1KDM4E | |
| SCHEMBL23163765 | 0.81 | MAPK1 (0.49) | PPIACTSVCTSLKMT2AALDH1A1 | |
| SCHEMBL29831476 | 0.81 | PIN1 (0.50) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL29831603 | 0.78 | MAPK14 (0.44) | PPIACTSVCTSLKMT2AALDH1A1 | |
| SCHEMBL23164307 | 0.78 | MAPK14 (0.44) | PPIACTSVCTSLKMT2AALDH1A1 | |
| SCHEMBL29831781 | 0.78 | AKT1 (0.52) | KMT2AALDH1A1MEN1LMNAPOLB | |
| SCHEMBL23163764 | 0.77 | KMT2A (0.44) | CTSVCTSLKMT2AALDH1A1MEN1 | |
| SCHEMBL29831611 | 0.77 | AKT1 (0.48) | KMT2AALDH1A1MEN1SMN1; SMN2LMNA | |
| SCHEMBL23163724 | 0.73 | PIN1 (0.48) | CTSVCTSLKMT2AALDH1A1MEN1 | |
| SCHEMBL2717131 | 0.72 | HPGD (0.69) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037770-A1 | NOVEL PYRIDIN-2(1H)ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF PAIN | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-08-10 | — | — | EP | disclosed |