Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291107 | 0.78 | PDE7A (0.50) | PDE7AALDH1A1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5435635 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL29408522 | 0.71 | PDE7A (0.48) | PDE7AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL32681347 | 0.70 | PDE7A (0.45) | PDE7AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2048115 | 0.66 | GRIK1 (0.50) | ALDH1A1MEN1KMT2AKDM4EGRIK1 | |
| SCHEMBL30837926 | 0.64 | PDE7A (0.73) | PDE7AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL843239 | 0.64 | PDE7A (0.73) | PDE7AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31177912 | 0.63 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL30273112 | 0.63 | KDM4E (0.54) | KDM4EFEN1 | |
| SCHEMBL30641970 | 0.62 | GRIK1 (0.46) | ALDH1A1MAPTMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115192711-A | Use of PDE7 inhibitors for the treatment of movement disorders | 奥默罗斯公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114984229-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | 奥默罗斯公司 | 2022-09-02 | — | — | CN | disclosed |