SCHEMBL29831996

SCHEMBL29831996

O=C(NN=Cc1ccncc1)c1cccc(C(=O)NN=Cc2ccncc2)n1

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.74
MEN1 O00255 4/20 0.74
NPC1 O15118 2/20 0.74
RAB9A P51151 2/20 0.74
L3MBTL1 Q9Y468 3/20 0.66
MCL1 Q07820 1/20 0.66
SMN1; SMN2 Q16637 5/20 0.61
POLB P06746 4/20 0.60
CYP2D6 P10635 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
MAPT P10636 3/20 0.59
LMNA P02545 2/20 0.59
GFER P55789 1/20 0.59
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21441798 1.00 KMT2A (0.74) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL29832139 0.85 MEN1 (0.62) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL21441790 0.85 MEN1 (0.62) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL21441769 0.85 MEN1 (0.62) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL29831613 0.85 MEN1 (0.62) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL18350635 0.84 KMT2A (0.70) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL19646148 0.82 KMT2A (0.67) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL2988108 0.80 MEN1 (0.82) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL2988105 0.80 MEN1 (0.82) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL21441763 0.80 MEN1 (0.68) KMT2AMEN1NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3774770-B1 NOVEL HYDRAZONE DERIVATIVES FOR PREVENTING OR TREATING EBV-RELATED CANCERS UNIV BRETAGNE OCCIDENTALE (FR) 2023-09-06 EP disclosed
US-11406631-B2 Hydrazone derivatives for preventing or treating EBV-related cancers UNIVERSITE DE BRETAGNE OCCIDENTALE 2022-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11406631-B2 Hydrazone derivatives for preventing or treating EBV-related cancers RB1, MALT1, NR3C1 KMT2A 965/4885MEN1 401/4885NPC1 891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.